Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 8/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31309667 | 0.83 | CHEK1 (0.57) | ROCK2ROCK1CDC42BPBSRCMAPK1 | |
| SCHEMBL3289568 | 0.75 | HTR2A (0.50) | NCF1ADRB2HTR6HTR2AHTR2C | |
| SCHEMBL1030420 | 0.72 | HTT (0.76) | SRCRECQLTP53MAPK1HTT | |
| SCHEMBL13391271 | 0.71 | NCF1 (0.55) | NCF1ADRB2HTR6ROCK2ROCK1 | |
| SCHEMBL1537943 | 0.71 | NCF1 (0.48) | NCF1ADRB2HTR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL1967814 | 0.70 | NCF1 (0.54) | NCF1ADRB2HTR6ROCK2ROCK1 | |
| SCHEMBL4178410 | 0.68 | NCF1 (0.52) | NCF1ADRB2HTR6HTR2AHTR2C | |
| SCHEMBL2799562 | 0.68 | AKT2 (0.67) | NCF1ADRB2HTR6ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL2800609 | 0.67 | AKT2 (0.65) | NCF1ADRB2HTR6ROCK2ROCK1 | |
| SCHEMBL6070124 | 0.67 | SRC (0.56) | SRCHTR2CTP53MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534796-B2 | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-19 | — | — | US | claimed |
| US-20060189617-A1 | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | claimed |
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-7534796-B2 | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| US-20060189617-A1 | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189617-A1 | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor | GNRHR, PRLHR, FSHR | NCF1 3715/4885ADRB2 504/4885HTR6 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.