Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317803 | 0.91 | ALOX5 (1.00) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6796057 | 0.82 | ALOX5 (0.76) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7826782 | 0.80 | ALOX5 (0.81) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7826833 | 0.79 | GAA (0.75) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7816219 | 0.75 | GAA (0.68) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7831253 | 0.74 | ALOX5 (0.67) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL31286098 | 0.74 | GAA (1.00) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL2005093 | 0.74 | GAA (1.00) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4557751 | 0.74 | ALOX5 (1.00) | ALOX5PTGES | |
| SCHEMBL11198914 | 0.72 | ALOX5 (0.56) | ALOX5MEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146696-A1 | USE OF INDOLE-3-CARBOXYLIC ESTERS FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE | Universität Tübingen (DE) | 2009-12-10 | — | — | WO | disclosed |