SCHEMBL4558544

SCHEMBL4558544

COC(=O)CCP(=O)(O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.60
TSHR P16473 1/20 0.59
POLB P06746 2/20 0.57
ALDH1A1 P00352 6/20 0.53
SMN1; SMN2 Q16637 3/20 0.44
PKM P14618 1/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 2/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
MAPT P10636 2/20 0.43
RAB9A P51151 1/20 0.43
AKT1 P31749 1/20 0.43
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290988 0.85 TSHR (0.50) CFTRTSHRPOLBALDH1A1LMNA
SCHEMBL7616535 0.83 SMN1; SMN2 (0.61) CFTRTSHRPOLBALDH1A1SMN1; SMN2
SCHEMBL5476527 0.81 POLB (0.56) CFTRTSHRPOLBALDH1A1SMN1; SMN2
SCHEMBL8606909 0.81 ALDH1A1 (0.55) CFTRTSHRPOLBALDH1A1SMN1; SMN2
SCHEMBL28393243 0.80 CFTR (0.45) CFTRTSHRPOLBALDH1A1SMN1; SMN2
Potassium Ion SCHEMBL28864278 0.80 POLB (0.54) CFTRTSHRPOLBALDH1A1SMN1; SMN2
SCHEMBL19773247 0.80 CFTR (0.72) CFTRTSHRALDH1A1KMT2AMEN1
SCHEMBL65139 0.80 CFTR (0.72) CFTRTSHRALDH1A1KMT2AMEN1
SCHEMBL28394902 0.79 CFTR (0.44) CFTRTSHRPOLBALDH1A1SMN1; SMN2
SCHEMBL5530286 0.79 CFTR (0.55) CFTRTSHRPOLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9124668-A None JP disclosed
CN-100567376-C Thermoplastic resin composition for master batch, process for producing molding material thereof, thermoplastic resin composition, and process for producing the same TOYO BOSEKI (JP) 2009-12-09 CN disclosed
CN-101397371-A Thermoplastic resin composition for master batch and process for producing molding material thereof TOYO BOSEKI (JP) 2009-04-01 CN disclosed
US-20090025144-A1 Flame-Retardant Bedding KANEKA CORPORATION (JP) 2009-01-29 US disclosed
US-20070194479-A1 Thermoplastic Resin Composition For Masterbatches, Method Of Producing Molding Material Thereof, And Thermoplastic Resin Composition Using Them And Method Of Production Thereof TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-08-23 US disclosed
CN-1890298-A Thermoplastic resin composition for master batch, process for producing molding material thereof, thermoplastic resin composition using the same, and process for producing the same TOYO BOSEKI (JP) 2007-01-03 CN disclosed
EP-1693403-A1 THERMOPLASTIC RESIN COMPOSITION FOR MASTERBATCH, PROCESS FOR PRODUCING MOLDING MATERIAL COMPRISING THE SAME, THERMOPLASTIC RESIN COMPOSITION OBTAINED WITH THE SAME, AND PROCESS FOR PRODUCING THE COMPOSITION Toyo Boseki Kabushiki Kaisha (JP) 2006-08-23 EP disclosed
EP-0742224-B1 PROCESS FOR PRODUCING ORGANOPHOSPHORUS ESTER COMPOUND AND REACTIVE FLAME RETARDANT SANYO CHEMICAL IND LTD (JP) 2002-05-02 EP disclosed
US-5710308-A Process for producing ogranophosphorus ester compound and reactive flame retardant SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1998-01-20 US disclosed
JP-H09124668-A PHOSPHORUS-CONTAINING ETHYLENIC UNSATURATED MONOMER AND FLAME-RETARDANT RESIN USING THE SAME SANYO CHEM IND LTD 1997-05-13 JP disclosed
EP-0742224-A1 PROCESS FOR PRODUCING ORGANOPHOSPHORUS ESTER COMPOUND AND REACTIVE FLAME RETARDANT SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-13 EP disclosed
US-5334760-A Reacting a dichlorophosphine compound with acrylic acid or methacrylic acid in presence of a peroxide or an azo catalysts then hydration SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-08-02 US disclosed