Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.32 |
| ▸ | WNT1 | P04628 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816095 | 0.91 | PARP1 (0.36) | PRMT5WDR77DRD1CYP3A4HTR2B | |
| SCHEMBL3815120 | 0.91 | DRD1 (0.37) | PRMT5WDR77GSK3BDYRK1ADRD1 | |
| SCHEMBL4192732 | 0.88 | QRFPR (0.35) | PRMT5WDR77GSK3BDYRK1ADRD1 | |
| SCHEMBL3818897 | 0.88 | GSK3B (0.37) | PRMT5WDR77GSK3BDYRK1AWNT1 | |
| SCHEMBL3813823 | 0.87 | GSK3B (0.38) | PRMT5WDR77GSK3BDYRK1AWNT1 | |
| SCHEMBL4559837 | 0.84 | DRD1 (0.34) | DRD1CYP3A4HTR2BCACNA1B | |
| SCHEMBL4551226 | 0.84 | GRM5 (0.43) | PRMT5WDR77GRM5 | |
| SCHEMBL3821199 | 0.83 | QRFPR (0.38) | PRMT5WDR77GSK3BDYRK1ADRD1 | |
| SCHEMBL3819778 | 0.83 | GSK3B (0.35) | PRMT5WDR77GSK3BDYRK1AWNT1 | |
| SCHEMBL3819025 | 0.81 | DRD1 (0.40) | DRD1CYP3A4HTR2BCACNA1BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |