Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613273 | 0.91 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1CA2CA12 | |
| SCHEMBL584830 | 0.91 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1CA2CA12 | |
| Bicarbonate SCHEMBL5604857 | 0.90 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1CA2CA12 | |
| SCHEMBL146742 | 0.88 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1CA2CA12 | |
| Bicarbonate SCHEMBL7096874 | 0.86 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1CA2CA12 | |
| Methacrylic Acid SCHEMBL7198982 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CA2CA12 | |
| Salicylic Acid SCHEMBL27672324 | 0.86 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1CA2CA12 | |
| Benzene SCHEMBL11421230 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1CA2CA12 | |
| SCHEMBL51085 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1CA2CA12 | |
| SCHEMBL11645702 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957572-B1 | METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE POLYMER | JSR CORP (JP) | 2020-04-08 | — | — | EP | disclosed |
| US-20150368387-A1 | METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE POLYMER | JSR CORPORATION (JP) | 2015-12-24 | — | — | US | disclosed |
| EP-2957572-A1 | METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE POLYMER | JSR Corporation (JP) | 2015-12-23 | — | — | EP | disclosed |
| EP-1600479-B1 | Resin composition and golf ball | JSR CORP (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-1245585-B1 | Hydrogenated modified polymer, process for producing the same and composition containing the same | JSR CORP (JP) | 2008-05-21 | — | — | EP | disclosed |
| EP-1600479-A1 | Resin composition and golf ball | JSR Corporation (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-1293535-B1 | Resin composition and golf ball | JSR CORP (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6887929-B2 | Resin composition and golf ball | JSR CORPORATION (JP) | 2005-05-03 | — | — | US | disclosed |
| US-6838538-B2 | Hydrogenated modified polymer, process for producing the same and composition containing the same | JSR CORPORATION (JP) | 2005-01-04 | — | — | US | disclosed |
| US-20030130425-A1 | Resin composition and golf ball | JSR CORPORATION (JP) | 2003-07-10 | — | — | US | disclosed |
| US-20030100683-A1 | Hydrogenated modified polymer, process for producing the same and composition containing the same | JSR CORPORATION (JP) | 2003-05-29 | — | — | US | disclosed |
| EP-1293535-A2 | Resin composition and golf ball | JSR Corporation (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-1245585-A2 | Hydrogenated modified polymer, process for producing the same and composition containing the same | JSR Corporation (JP) | 2002-10-02 | — | — | EP | disclosed |