SCHEMBL4558607

SCHEMBL4558607

CCCCCOc1c(C)nc(C)c(O)c1O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.41
LTA4H P09960 1/20 0.39
ESR1 P03372 3/20 0.37
THRA P10827 4/20 0.36
THRB P10828 4/20 0.36
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
TLR4 O00206 3/20 0.35
GPR84 Q9NQS5 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14141549 0.76 NR5A1 (0.46) NR5A1LTA4HESR1AKR1C4AKR1C3
SCHEMBL5587840 0.74 NR5A1 (0.43) NR5A1LTA4HESR1THRATHRB
SCHEMBL5589247 0.73 NR5A1 (0.46) NR5A1LTA4HESR1THRATHRB
SCHEMBL5588645 0.73 NR5A1 (0.46) NR5A1LTA4HESR1THRATHRB
SCHEMBL5586826 0.73 NR5A1 (0.46) NR5A1LTA4HESR1THRATHRB
SCHEMBL5587623 0.73 NR5A1 (0.46) NR5A1LTA4HESR1THRATHRB
SCHEMBL5588635 0.73 NR5A1 (0.46) NR5A1LTA4HESR1THRATHRB
SCHEMBL19127440 0.72 NR5A1 (0.42) NR5A1LTA4HESR1AKR1C4AKR1C3
SCHEMBL29059209 0.72 ESR1 (0.53) NR5A1ESR1THRATHRBAKR1C4
SCHEMBL5589363 0.71 ALOX5 (0.43) NR5A1LTA4HESR1THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7495101-B2 Manufacture of vitamin B6 DSM IP ASSETS B.V. (NL) 2009-02-24 US disclosed
US-20070072254-A1 Manufacture of vitamin b6 DSM IP ASSETS B.V. (NL) 2007-03-29 US disclosed
EP-1685133-A1 MANUFACTURE OF VITAMIN B6 DSM IP Assets B.V. (NL) 2006-08-02 EP disclosed
WO-2005049618-A1 MANUFACTURE OF VITAMIN B6 DSM IP ASSETS B.V. (NL) 2005-06-02 WO disclosed