Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30004036 | 0.77 | APEX1 (0.52) | APEX1KDM4EALDH1A1GLAADORA2B | |
| SCHEMBL5329443 | 0.74 | APEX1 (0.82) | APEX1KDM4EALDH1A1POLBGLA | |
| SCHEMBL3591763 | 0.70 | KDM4E (0.42) | APEX1KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL4560787 | 0.70 | GRIN2D (0.42) | APEX1KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL677187 | 0.70 | APEX1 (0.62) | APEX1KDM4EALDH1A1GLAADORA2B | |
| SCHEMBL29251527 | 0.69 | APEX1 (0.53) | APEX1KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL12357459 | 0.68 | APEX1 (0.41) | APEX1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL12357451 | 0.68 | APEX1 (0.44) | APEX1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL3374638 | 0.68 | APEX1 (0.65) | APEX1KDM4EALDH1A1MAPTGLA | |
| SCHEMBL24666582 | 0.68 | KDM4E (0.44) | APEX1KDM4EALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |