Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.67 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.67 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.67 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | PARP1 | P09874 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367508 | 1.00 | KDM4E (0.67) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL37951 | 1.00 | KDM4E (0.67) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL4647780 | 0.97 | KDM4E (0.63) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL30275219 | 0.97 | KDM4E (0.63) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL30832797 | 0.97 | KDM4E (0.63) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14290240 | 0.84 | PDE3B (0.54) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28765354 | 0.83 | KDM4E (0.48) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30230748 | 0.81 | KDM4E (0.52) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| Piperidine SCHEMBL8059402 | 0.81 | KDM4E (0.47) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL239920 | 0.80 | KDM4E (1.00) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557175-B2 | Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-07-07 | — | — | US | disclosed |