Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28895351 | 0.79 | — | — | |
| SCHEMBL9309423 | 0.76 | TSHR (0.53) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL28748702 | 0.75 | TSHR (0.45) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL10352080 | 0.75 | TSHR (0.51) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL3795921 | 0.75 | — | — | |
| SCHEMBL28939437 | 0.75 | SCN2A (0.31) | — | |
| SCHEMBL9221239 | 0.74 | TSHR (0.50) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL29185348 | 0.74 | — | — | |
| SCHEMBL2799211 | 0.73 | TSHR (0.53) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL28807732 | 0.73 | SCN2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994005749-A1 | HIGH STRENGTH, LOW CONDUCTIVITY ELECTRORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1994-03-17 | — | — | WO | claimed |
| EP-2105454-B1 | Thioether functionalised organopolysiloxanes | SCHILL & SEILACHER STRUKTOL GMBH (DE) | 2012-09-12 | — | — | EP | disclosed |
| EP-2105454-A1 | Thioether functionalised organopolysiloxanes | Schill + Seilacher "Struktol" Aktiengesellschaft (DE) | 2009-09-30 | — | — | EP | disclosed |