Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352080 | 0.99 | TSHR (0.51) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL2799211 | 0.97 | TSHR (0.53) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL8512777 | 0.91 | TSHR (0.47) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL8815356 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL9308723 | 0.77 | MAPT (0.31) | — | |
| SCHEMBL2851476 | 0.77 | MEN1 (0.34) | TSHRMAPK1 | |
| SCHEMBL9308300 | 0.77 | TSHR (0.33) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL4558741 | 0.76 | TSHR (0.49) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL6828574 | 0.76 | MEN1 (0.37) | TSHRMAPK1 | |
| SCHEMBL2239338 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004259-A1 | POLYSILOXANE EMULSIONS | PPG INDUSTRIES, INC. (US) | 1994-03-03 | — | — | WO | claimed |
| EP-0383835-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-08-29 | — | — | EP | claimed |
| WO-1989003851-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-05-05 | — | — | WO | claimed |
| US-5372854-A | Maintaining uniform moisture content in cotton bales by spraying before compression with a dimethylsiloxane homo- or copolymer | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1994-12-13 | — | — | US | disclosed |
| EP-0468626-B1 | Cotton bales and method of producing same | TAKEMOTO OIL & FAT CO LTD (JP) | 1994-06-01 | — | — | EP | disclosed |
| WO-1994004259-A1 | POLYSILOXANE EMULSIONS | PPG INDUSTRIES, INC. (US) | 1994-03-03 | — | — | WO | disclosed |
| US-5188224-A | Water insoluble, protective coating of polysiloxane adhesive coating attached to lint cotton | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0383835-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-08-29 | — | — | EP | disclosed |
| WO-1989003851-A1 | SURFACE-ACTIVE POLYSILOXANES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-05-05 | — | — | WO | disclosed |