Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315471 | 0.81 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1PDPK1 | |
| SCHEMBL11310918 | 0.81 | PDPK1 (0.53) | MEN1KMT2AALDH1A1PDPK1CA1 | |
| SCHEMBL7651926 | 0.80 | KMT2A (0.67) | MEN1KMT2AMAPTALDH1A1PDPK1 | |
| SCHEMBL3219943 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AMAPTALDH1A1PDPK1 | |
| SCHEMBL4700260 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AMAPTALDH1A1PDPK1 | |
| SCHEMBL18539280 | 0.77 | PDPK1 (0.66) | PDPK1CA1CA2SLC18A3MAOA | |
| SCHEMBL1691714 | 0.77 | PDPK1 (0.66) | PDPK1CA1CA2SLC18A3MAOA | |
| SCHEMBL31388654 | 0.77 | PDPK1 (0.66) | PDPK1CA1CA2SLC18A3MAOA | |
| SCHEMBL2073072 | 0.77 | CA1 (0.57) | MEN1KMT2AMAPTALDH1A1PDPK1 | |
| SCHEMBL1441195 | 0.77 | CA1 (0.57) | MEN1KMT2AMAPTALDH1A1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101312945-A | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2008-11-26 | — | — | CN | claimed |
| WO-2012033601-A1 | THIOSEMICARBAZONES WITH MDR1 - INVERSE ACTIVITY | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2012-03-15 | — | — | WO | disclosed |
| CN-101312945-A | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2008-11-26 | — | — | CN | disclosed |