Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.91 |
| ▸ | NPC1 | O15118 | 5/20 | 0.91 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097729 | 0.87 | RAB9A (0.74) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL672008 | 0.84 | RAB9A (0.75) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL19180399 | 0.83 | RAB9A (0.73) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL17346760 | 0.83 | RAB9A (0.78) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL25668726 | 0.83 | RAB9A (0.73) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL1575749 | 0.81 | NPC1 (0.70) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL25668730 | 0.81 | RAB9A (0.71) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL9283129 | 0.80 | RAB9A (0.65) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL1610477 | 0.80 | RAB9A (0.65) | RAB9ANPC1HTTL3MBTL1KDM4E | |
| SCHEMBL1574714 | 0.80 | RAB9A (0.72) | RAB9ANPC1HTTL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137549-A1 | Novel compounds useful for the treatment of degenerative & inflamatory diseases | GALAPAGOS NV (BE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137549-A1 | Novel compounds useful for the treatment of degenerative & inflamatory diseases | PDE4A, PDE7B, PDE4B | RAB9A 1318/4885NPC1 3876/4885HTT 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.