Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306333 | 0.85 | CHRM3 (0.55) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| SCHEMBL4344039 | 0.80 | CHRM3 (0.52) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Bicarbonate SCHEMBL4306338 | 0.80 | CHRM3 (0.58) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| SCHEMBL4154195 | 0.80 | CHRM3 (0.58) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| SCHEMBL6938003 | 0.79 | CHRM3 (0.63) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL27510671 | 0.79 | CHRM3 (0.66) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Isobutane SCHEMBL4559917 | 0.79 | CHRM3 (0.57) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL5179503 | 0.78 | CHRM3 (0.62) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL27530654 | 0.78 | CHRM3 (0.62) | CHRM3ADRB2CHRM2CHRM1CHRM5 | |
| SCHEMBL4150848 | 0.78 | CHRM3 (0.62) | CHRM3ADRB2CHRM2CHRM1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612084-B2 | Amine derivatives for the treatment of asthma and COPD | PFIZER INC (US) | 2009-11-03 | — | — | US | disclosed |
| US-20070265303-A1 | Amine derivatives | PFIZER LIMITED | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265303-A1 | Amine derivatives | HNMT, HRH4, CMA1 | CHRM3 169/4885ADRB2 93/4885CHRM2 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.