Xanthone

Xanthone

SCHEMBL4560050

O=c1c2ccccc2oc2ccccc12.[Si]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 9/20 0.95
KDM4E B2RXH2 3/20 0.95
ALDH1A1 P00352 3/20 0.95
GLA P06280 1/20 0.95
CYP3A4 P08684 1/20 0.95
MAPT P10636 1/20 0.95
HPGD P15428 1/20 0.95
PGAM1 P18669 1/20 0.95
CASP1 P29466 1/20 0.95
CASP7 P55210 1/20 0.95
SMN1; SMN2 Q16637 1/20 0.95
HSD17B10 Q99714 1/20 0.95
NPC1 O15118 6/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
RAB9A P51151 5/20 0.58
TTR P02766 2/20 0.58
LMNA P02545 1/20 0.58
NTRK1 P04629 1/20 0.57
PLK3 Q9H4B4 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthone SCHEMBL18556112 1.00 MAOA (0.95) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL29398266 0.97 MAOA (1.00) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL29358061 0.97 MAOA (1.00) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL41161 0.97 MAOA (1.00) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL2354794 0.97 MAOA (1.00) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL11399893 0.95 MAOA (0.95) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL31110616 0.95 MAOA (0.95) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL29142621 0.95 MAOA (0.95) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL5376736 0.95 MAOA (0.95) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL29060570 0.95 MAOA (0.95) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US disclosed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US disclosed