Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 3/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669696 | 0.81 | KDM4E (0.52) | KDM4EATAD2DAOGDAMEN1 | |
| SCHEMBL763349 | 0.78 | GRIA1 (0.52) | KDM4EDAODDOGRIA1CACNG8 | |
| SCHEMBL3227967 | 0.76 | PDE3B (0.45) | KDM4EDAOMEN1MAPTKMT2A | |
| SCHEMBL14891503 | 0.75 | KDM4E (0.42) | KDM4EATAD2GDAMEN1MAPT | |
| Hydrochloric Acid SCHEMBL11468924 | 0.74 | PDE3B (0.44) | KDM4EDAOMEN1MAPTKMT2A | |
| SCHEMBL9588762 | 0.73 | DAO (0.33) | KDM4ECA1DAODDO | |
| SCHEMBL2919116 | 0.73 | CHEK1 (0.53) | KDM4EDAOMEN1MAPTKMT2A | |
| SCHEMBL1503032 | 0.73 | BRD4 (0.48) | DAOGDAPDE3BPDE3A | |
| SCHEMBL7031010 | 0.73 | STING1 (0.43) | KDM4EATAD2DAOGDAMAPT | |
| SCHEMBL6674677 | 0.72 | NQO2 (0.54) | KDM4ETP53MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102464654-B | Antiviral compound | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2016-01-13 | — | — | CN | disclosed |
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |