Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15825041 | 0.89 | NQO2 (0.56) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL6671371 | 0.88 | NQO2 (0.56) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL21230826 | 0.81 | CYP19A1 (0.45) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL17883981 | 0.81 | CYP19A1 (0.45) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL6669696 | 0.81 | KDM4E (0.52) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL25647633 | 0.78 | NQO2 (0.45) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL25329522 | 0.76 | NQO2 (0.46) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL6672275 | 0.76 | CYP19A1 (0.46) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL14891503 | 0.75 | KDM4E (0.42) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL26550995 | 0.73 | PDE3B (0.46) | NQO2CYP19A1KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401830-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | disclosed |