Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962280 | 0.76 | ESR1 (0.43) | CAPN1ALDH1A1KMT2AMEN1SLC6A2 | |
| SCHEMBL27656915 | 0.75 | CAPN1 (0.39) | CAPN1ALDH1A1KMT2ATRPM8CYP3A4 | |
| SCHEMBL517462 | 0.74 | SMN1; SMN2 (0.57) | ALDH1A1BLMCYP1A2CYP3A4RECQL | |
| SCHEMBL30599583 | 0.73 | CAPN1 (0.47) | CAPN1ALDH1A1KMT2ATRPM8CYP1A2 | |
| SCHEMBL28727407 | 0.72 | SMN1; SMN2 (0.55) | ALDH1A1BLMCYP1A2CYP3A4RECQL | |
| SCHEMBL28246706 | 0.72 | HIF1A (0.55) | ALDH1A1KMT2ABLMCYP1A2CYP3A4 | |
| SCHEMBL27925093 | 0.72 | ESR1 (0.56) | ALDH1A1KMT2ABLMKDM4EL3MBTL1 | |
| SCHEMBL2754652 | 0.72 | TSHR (0.43) | CAPN1ALDH1A1KMT2ABLMCYP1A2 | |
| SCHEMBL11596247 | 0.71 | BLM (0.67) | ALDH1A1KMT2ABLMKDM4ECYP4F2 | |
| SCHEMBL6668736 | 0.71 | BLM (0.52) | ALDH1A1KMT2ABLMKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781444-A | Antitumor agent or postoperative adjuvant chemotherapeutic agent for treatment of hepatocellular carcinoma | TAIHO PHARMACEUTICAL CO LTD | 2012-11-14 | — | — | CN | claimed |
| CN-102724981-A | Method for predicting treatment effect of chemotherapy on hepatocellular carcinoma patient | TAIHO PHARMACEUTICAL CO LTD | 2012-10-10 | — | — | CN | claimed |
| EP-2637649-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | Akron Molecules GmbH (AT) | 2013-09-18 | — | — | EP | disclosed |
| CN-102781444-A | Antitumor agent or postoperative adjuvant chemotherapeutic agent for treatment of hepatocellular carcinoma | TAIHO PHARMACEUTICAL CO LTD | 2012-11-14 | — | — | CN | disclosed |
| CN-102724981-A | Method for predicting treatment effect of chemotherapy on hepatocellular carcinoma patient | TAIHO PHARMACEUTICAL CO LTD | 2012-10-10 | — | — | CN | disclosed |
| WO-2012062925-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |