SCHEMBL517462

SCHEMBL517462

CC(C)(Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.57
HIF1A Q16665 1/20 0.57
SLC6A2 P23975 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
CYP3A4 P08684 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.48
CYP2D6 P10635 1/20 0.48
RIPK1 Q13546 3/20 0.47
TRPA1 O75762 1/20 0.47
MMP8 P22894 3/20 0.46
CYP1A2 P05177 2/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
FDPS P14324 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28246706 0.98 HIF1A (0.55) SMN1; SMN2HIF1ASLC6A2TAAR1CYP3A4
SCHEMBL28727407 0.98 SMN1; SMN2 (0.55) SMN1; SMN2HIF1ASLC6A2TAAR1CYP3A4
SCHEMBL30853559 0.90 TRPA1 (0.49) SMN1; SMN2HIF1ASLC6A2TAAR1CYP3A4
SCHEMBL5171029 0.88 ABCC4 (0.52) SMN1; SMN2HIF1ACYP2C9ALDH1A1LMNA
SCHEMBL14740848 0.87 CYP1A2 (0.45) SMN1; SMN2HIF1ASLC6A2TAAR1CYP3A4
SCHEMBL1147656 0.86 SLC6A2 (0.52) SMN1; SMN2HIF1ASLC6A2TAAR1CYP3A4
SCHEMBL29368049 0.85 CYP1A2 (0.44) SMN1; SMN2HIF1ACYP3A4CYP2C19PPARG
SCHEMBL6722173 0.84 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ASLC6A2TAAR1CYP3A4
SCHEMBL27925093 0.84 ESR1 (0.56) SMN1; SMN2HIF1ACYP3A4PPARGPPARA
SCHEMBL8759 0.84 SLC6A2 (0.56) SMN1; SMN2HIF1ASLC6A2TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 740 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901653-B Novel amide derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof 株式会社LG化学 2024-11-22 CN claimed
CN-114901653-A Novel amide derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof 株式会社LG化学 2022-08-12 CN claimed
EP-3387099-B1 FOOD CONTACT SURFACE SANITIZING LIQUID CLOROX CO (US) 2021-07-21 EP claimed
EP-3688124-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2020-08-05 EP claimed
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-07-14 US claimed
EP-3423028-B1 METHOD FOR THE PRODUCTION OF ENCAPSULATED FRAGRANCE WITH IMPROVED STABILITY AGAINST DETERGENTS SYMRISE AG (DE) 2020-04-08 EP claimed
EP-3006547-B1 FRAGRANCE-CONTAINING CAPSULE AND COSMETIC IN WHICH SAID CAPSULES ARE BLENDED SHISEIDO CO LTD (JP) 2019-10-30 EP claimed
WO-2019067061-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-04-04 WO claimed
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-04-04 US claimed
EP-3423028-A1 METHOD FOR THE PRODUCTION OF SCENT CAPSULES WITH IMPROVED SURFACTANT STABLITY Symrise AG (DE) 2019-01-09 EP claimed
US-20180119045-A1 HIGH VISCOSITY INDEX MONOMETHYL ESTER LUBRICATING OIL BASE STOCKS AND METHODS OF MAKING AND USE THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2018-05-03 US claimed
WO-2017116900-A1 HIGH VISCOSITY INDEX MONOMETHYL ESTER LUBRICATING OIL BASE STOCKS AND METHODS OF MAKING AND USE THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-07-06 WO claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-6451334-B2 PULSE ADMINISTERING OF A C1-C4 SUBSTITUTED AND/OR PHENYL SUBSTITUTED CARBOXYLIC ACID AND SALTS AND A CARRIER OR DILUENT TO STIMULATE CELLS IN TREATING BLOOD DISORDERS, E.G. SICKLE CELL ANEMIA, THALASSEMIA, BLOOD LOSS ETC. Perrine, Susan P. 2002-09-17 US claimed
EP-0812538-B1 Preservative compositions ANGUS CHEMICAL (US) 2001-01-03 EP claimed
EP-0861072-A2 COMPOSITIONS FOR THE TREATMENT OF BLOOD DISORDERS TRUSTEES OF BOSTON UNIVERSITY (US) 1998-09-02 EP claimed
WO-1996027369-A9 COMPOSITIONS FOR THE TREATMENT OF BLOOD DISORDERS 1996-12-27 WO claimed
WO-1996027369-A2 COMPOSITIONS FOR THE TREATMENT OF BLOOD DISORDERS THE TRUSTEES OF BOSTON UNIVERSITY (US) 1996-09-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same ELOVL1, NOTUM, ELOVL5 SMN1; SMN2 853/4885HIF1A 4509/4885SLC6A2 3650/4885
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same ELOVL1, NOTUM, ELOVL5 SMN1; SMN2 853/4885HIF1A 4509/4885SLC6A2 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.