Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 9/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459489 | 0.81 | PIM1 (0.35) | PIM1PIM2CHRNB2CHRNA4 | |
| SCHEMBL25071608 | 0.78 | PIM1 (0.38) | PIM1PIM2CHRNB2CHRNA4 | |
| SCHEMBL21722806 | 0.67 | PIM1 (0.41) | PIM1PIM2IRAK4 | |
| SCHEMBL26081211 | 0.67 | DRD2 (0.36) | — | |
| SCHEMBL23047362 | 0.67 | TDP1 (0.53) | CHRNB2CHRNA4 | |
| SCHEMBL1959260 | 0.67 | IRAK4 (0.38) | LRRK2IRAK4 | |
| SCHEMBL30820798 | 0.66 | CHRNA7 (0.49) | — | |
| Hydrochloric Acid SCHEMBL28529877 | 0.66 | PIM1 (0.41) | PIM1PIM2IRAK4 | |
| SCHEMBL14782795 | 0.66 | LRRK2 (0.41) | LRRK2IRAK4 | |
| Hydrochloric Acid SCHEMBL15540086 | 0.66 | TDP1 (0.55) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |