Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15611076 | 0.90 | RORC (0.83) | RORC | |
| SCHEMBL15611075 | 0.90 | RORC (0.83) | RORC | |
| SCHEMBL4566365 | 0.81 | RORC (0.79) | RORC | |
| SCHEMBL15625847 | 0.81 | RORC (0.90) | RORC | |
| SCHEMBL5022488 | 0.80 | RORC (1.00) | RORC | |
| SCHEMBL15610937 | 0.80 | RORC (1.00) | RORC | |
| SCHEMBL15625843 | 0.80 | RORC (1.00) | RORC | |
| SCHEMBL4562430 | 0.80 | RORC (0.57) | RORC | |
| SCHEMBL5023721 | 0.79 | RORC (0.65) | RORC | |
| SCHEMBL15625863 | 0.79 | RORC (0.85) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638014-A2 | TETRAHYDROQUINOLINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF ROR ACTIVITY AND THE TREATMENT OF DISEASE | Lycera Corporation (US) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064744-A2 | TETRAHYDROQUINOLINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORϒ ACTIVITY AND THE TREATMENT OF DISEASE | LYCERA CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |