Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118759 | 1.00 | TYK2 (0.34) | TYK2HTR2CRAB9AALOX5APFEN1 | |
| SCHEMBL3114743 | 1.00 | TYK2 (0.34) | TYK2HTR2CRAB9AALOX5APFEN1 | |
| SCHEMBL1266738 | 0.85 | POLB (0.35) | RAB9ACYP3A4SLC16A1ADORA2AADORA2B | |
| SCHEMBL1267126 | 0.85 | POLB (0.35) | RAB9ACYP3A4SLC16A1ADORA2AADORA2B | |
| SCHEMBL1266545 | 0.82 | NOTUM (0.34) | HTR2CRAB9ACYP3A4CYP2C9SLC16A1 | |
| SCHEMBL1266692 | 0.82 | NOTUM (0.34) | HTR2CRAB9ACYP3A4CYP2C9SLC16A1 | |
| SCHEMBL1265818 | 0.81 | ALDH1A1 (0.36) | HTR2CRAB9ACYP3A4CYP2C9SLC16A1 | |
| SCHEMBL1265514 | 0.81 | ALDH1A1 (0.36) | HTR2CRAB9ACYP3A4CYP2C9SLC16A1 | |
| SCHEMBL3113159 | 0.81 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL3113114 | 0.81 | MAPK14 (0.33) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099805-A2 | NOVEL AMINOTHIENOPYRIDINONE DERIVATIVES PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS THEREOF | UCB Pharma S.A. (BE) | 2009-09-16 | — | — | EP | claimed |
| WO-2008064829-A2 | NOVEL AMINOTHIENOPYRIDINONE DERIVATIVES PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS THEREOF | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |