Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521900 | 0.87 | BLM (0.49) | RIPK1BLMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28690512 | 0.87 | BLM (0.49) | RIPK1BLMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL12679276 | 0.87 | BLM (0.49) | RIPK1BLMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL427855 | 0.87 | BLM (0.49) | RIPK1BLMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL427854 | 0.87 | BLM (0.49) | RIPK1BLMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL427045 | 0.81 | BLM (0.50) | BLMALDH1A1KDM4ECYP1A2MEN1 | |
| SCHEMBL427046 | 0.81 | BLM (0.50) | BLMALDH1A1KDM4ECYP1A2MEN1 | |
| SCHEMBL11402957 | 0.76 | ADRA1A (0.53) | BLMALDH1A1KDM4ECYP1A2MEN1 | |
| SCHEMBL11402961 | 0.76 | ADRA1A (0.53) | BLMALDH1A1KDM4ECYP1A2MEN1 | |
| SCHEMBL23009700 | 0.76 | BLM (0.51) | BLMALDH1A1KDM4ECYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084182-A2 | ANTIDIABETIC COMPOUNDS | Cadila Healthcare Limited (IN) | 2009-08-05 | — | — | EP | claimed |
| WO-2008062457-A2 | ANTIDIABETIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |