Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22130034 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HSD17B10PTGS2GAAMAPT | |
| SCHEMBL379153 | 0.91 | — | — | |
| SCHEMBL30564576 | 0.88 | ALDH1A1 (0.39) | ALDH1A1HSD17B10PTGS2GAAMAPT | |
| SCHEMBL29088267 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL9004846 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL28498396 | 0.88 | — | — | |
| Urea SCHEMBL27701208 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HSD17B10PTGS2GAAMAPT | |
| SCHEMBL9491675 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HSD17B10PTGS2HPGD | |
| Thiosemicarbazide SCHEMBL9222911 | 0.81 | ALDH1A1 (0.77) | ALDH1A1HSD17B10PTGS2HPGDGAA | |
| Thiosemicarbazide SCHEMBL28586936 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968651-B1 | STABILIZED COMPOSITIONS AND METHODS FOR RADIOLABELING PHARMACEUTICALS WITH ALPHA-PARTICLE EMITTERS | UNIV DUKE (US) | 2013-03-13 | — | — | EP | disclosed |
| US-8337810-B2 | Stabilized compositions and methods for radiolabeling pharmaceuticals with alpha-particle emitters | DUKE UNIVERSITY (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090304585-A1 | Stabilized Compositions and Methods for Radiolabeling Pharmaceuticals with Alpha-Particle Emitters | DUKE UNIVERSITY (US) | 2009-12-10 | — | — | US | disclosed |
| EP-1968651-A2 | STABILIZED COMPOSITIONS AND METHODS FOR RADIOLABELING PHARMACEUTICALS WITH ALPHA-PARTICLE EMITTERS | Duke University (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007120251-A2 | STABILIZED COMPOSITIONS AND METHODS FOR RADIOLABELING PHARMACEUTICALS WITH ALPHA-PARTICLE EMITTERS | DUKE UNIVERSITY (US) | 2007-10-25 | — | — | WO | disclosed |