SCHEMBL4562965

SCHEMBL4562965

C=CCC(N)(CO)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101392 0.94 MEN1 (0.50)
SCHEMBL361077 0.81 ALDH1A1 (0.38)
SCHEMBL1702483 0.78 TSHR (0.33)
SCHEMBL4534531 0.78 TSHR (0.33)
Bromide SCHEMBL4276596 0.78 ALDH1A1 (0.35)
Water SCHEMBL5407251 0.78 ALDH1A1 (0.35)
Hydrochloric Acid SCHEMBL142823 0.78 ALDH1A1 (0.35)
Hydrochloric Acid SCHEMBL4327791 0.76 TSHR (0.32)
Tromethamine SCHEMBL2021309 0.75 MEN1 (0.67)
Tromethamine SCHEMBL11125235 0.74 MEN1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-53037794-A None JP disclosed
CN-108530266-A A kind of alkynyl heptandiol class compound and its preparation method and application 湖南科技大学 2018-09-14 CN disclosed
US-9345791-B2 Ligands for targeting of S1P receptors for in vivo imaging and treatment of diseases WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) 2016-05-24 US disclosed
EP-2744776-A1 NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES Westfälische Wilhelms-Universität Münster (DE) 2014-06-25 EP disclosed
US-20140170067-A1 NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) 2014-06-19 US disclosed
WO-2013026765-A1 NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) 2013-02-28 WO disclosed
US-20090042772-A1 COMPOUNDS AND METHODS OF TREATING INSULIN RESISTANCE AND CARDIOMYOPATHY TRANSITION THERAPEUTICS INC. (CA) 2009-02-12 US disclosed
WO-2008083280-A1 COMPOUNDS AND METHODS OF TREATING INSULIN RESISTANCE AND CARDIOMYOPATHY TRANSITION THERAPEUTICS INC. (CA) 2008-07-10 WO disclosed
US-20080139455-A1 COMPOUNDS AND METHODS OF TREATING METABOLIC SYNDROME AND INFLAMMATION FORBES MEDI-TECH (RESEARCH), INC. (US) 2008-06-12 US disclosed
US-20080096799-A1 COMPOUNDS FOR AND METHODS OF TREATING INSULIN RESISTANCE AND INFLAMMATION FORBES MEDI-TECH (RESEARCH), INC. (US) 2008-04-24 US disclosed
US-5719176-A 2-amino-1,3-propanediol compound and immunosuppressant YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1998-02-17 US disclosed
US-5604229-A 2-amino-1,3-propanediol compound and immunosuppressant YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-02-18 US disclosed
US-5422042-A Improved toughness and flexibility HUNTSMAN CORPORATION (US) 1995-06-06 US disclosed
EP-0627406-A1 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1994-12-07 EP disclosed
EP-0233276-B1 WRAPPING THE CROWELL CORPORATION (US) 1992-01-29 EP disclosed
EP-0233276-A4 WRAPPING. CROWELL CORP (US) 1988-12-15 EP disclosed
EP-0233276-A1 WRAPPING. CROWELL CORP (US) 1987-08-26 EP disclosed
WO-1987001092-A1 WRAPPING THE CROWELL CORPORATION (US) 1987-02-26 WO disclosed
JP-S5337794-A PREPARATION OF AMINO RESIN OF LOW FREE-FORMALDEHYDE CONTENT HITACHI CHEM CO LTD 1978-04-07 JP disclosed
US-3976441-A Substituted aminoalkylpropanediol and motor fuel composition containing same TEXACO INC. (US) 1976-08-24 US disclosed