Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL14121026 | 1.00 | EP300 (0.36) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL278010 | 0.99 | EP300 (0.36) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL30600023 | 0.99 | EP300 (0.36) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL16195480 | 0.82 | EP300 (0.35) | EP300ALDH1A1LMNAMAPTGAA | |
| Ammonia Solution, Strong SCHEMBL28851102 | 0.82 | ALDH1A1 (0.33) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL7585449 | 0.81 | ALDH1A1 (0.33) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL28927324 | 0.81 | ALDH1A1 (0.34) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL361931 | 0.80 | ALDH1A1 (0.34) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL6421977 | 0.80 | ALDH1A1 (0.34) | EP300ALDH1A1LMNAMAPTGAA | |
| SCHEMBL969169 | 0.80 | ALDH1A1 (0.34) | EP300ALDH1A1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085090-B1 | IgA NEPHROPATHY-ASSOCIATED DNA | UNIV NIHON (JP) | 2011-12-14 | — | — | EP | disclosed |
| EP-2077275-A2 | IgA nephropathy-related DNA | Nihon University (JP) | 2009-07-08 | — | — | EP | disclosed |
| EP-1975175-A2 | IgA nephropathy-related DNA | Nihon University (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-6962984-B2 | DNA whose expression level fluctuates in leukocytes of IgA nephropathy patients in comparison with leukocytes of healthy persons, a process for isolating the DNA, a novel protein encoded by the DNA, an antibody recognizing the protein, | NIHON UNIVERSITY (JP) | 2005-11-08 | — | — | US | disclosed |
| US-20050048602-A1 | Kidney repairing factor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| US-20030207828-A1 | DNA whose expression level fluctuates in leukocytes of IgA nephropathy patients in comparison with leukocytes of healthy persons, a process for isolating the DNA, a novel protein encoded by the DNA, an antibody recognizing the protein, | NIHON UNIVERSITY (JP) | 2003-11-06 | — | — | US | disclosed |
| EP-1085090-A1 | IgA NEPHROPATHY-ASSOCIATED DNA | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |