Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193396 | 0.86 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3193150 | 0.83 | HRH3 (1.00) | HRH3ADRA2AADRA1D | |
| SCHEMBL3192205 | 0.82 | HRH3 (1.00) | HRH3ADRA2AADRA1D | |
| SCHEMBL3208982 | 0.81 | HRH3 (0.72) | HRH3ADRA2AADRA1D | |
| SCHEMBL3193123 | 0.76 | HRH3 (1.00) | HRH3ADRA2AADRA1D | |
| SCHEMBL3206922 | 0.76 | HRH3 (0.61) | HRH3 | |
| SCHEMBL3199073 | 0.74 | HRH3 (1.00) | HRH3ADRA2AADRA1D | |
| SCHEMBL3192212 | 0.70 | HRH3 (1.00) | HRH3ADRA2AADRA1D | |
| SCHEMBL3210836 | 0.70 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3198458 | 0.69 | HRH3 (1.00) | HRH3ADRA2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152071-A1 | UNNATURAL DISPYRIN ANALOGUES, PREPARATION AND USES THEREOF | VANDERBILT UNIVERSITY (US) | 2009-12-17 | — | — | WO | disclosed |