SCHEMBL4563274

SCHEMBL4563274

C=CCC1([SiH2]c2ccccc2)CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL463561 0.86 MEN1 (0.31) MEN1KMT2AALDH1A1POLBL3MBTL1
SCHEMBL6536454 0.80 ALDH1A1 (0.31) ALDH1A1L3MBTL1
SCHEMBL28060933 0.80 DPP4 (0.40)
SCHEMBL9302212 0.75
SCHEMBL8087905 0.74
SCHEMBL3772352 0.73
SCHEMBL27537081 0.73
SCHEMBL253428 0.73
SCHEMBL2640859 0.73
SCHEMBL19921938 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150054425-A1 NANOCOMPOSITE COMPOSITIONS AND METHODS OF MAKING CREELED, INC. 2015-02-26 US claimed
EP-0791190-B1 SIGNAGE ARTICLES AND METHODS OF MAKING SAME MINNESOTA MINING & MFG (US) 1999-09-29 EP claimed
US-20150054425-A1 NANOCOMPOSITE COMPOSITIONS AND METHODS OF MAKING CREELED, INC. 2015-02-26 US disclosed
EP-1846056-B1 MEDICAL DEVICES HAVING POROUS POLYMERIC REGIONS FOR CONTROLLED DRUG DELIVERY AND REGULATED BIOCOMPATIBILITY BOSTON SCIENT LTD (BB) 2014-10-08 EP disclosed
US-8535702-B2 Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-09-17 US disclosed
US-20090028897-A1 COSMETIC USE OF AN ACTIVE AGENT CAPABLE OF STIMULATING TENSIN 1 EXPRESSION CHANEL PARFUMS BEAUTE (FR) 2009-01-29 US disclosed
EP-1846056-A2 MEDICAL DEVICES HAVING POROUS POLYMERIC REGIONS FOR CONTROLLED DRUG DELIVERY AND REGULATED BIOCOMPATIBILITY Boston Scientific Scimed, Inc. (US) 2007-10-24 EP disclosed
WO-2006083904-A2 MEDICAL DEVICES HAVING POROUS POLYMERIC REGIONS FOR CONTROLLED DRUG DELIVERY AND REGULATED BIOCOMPATIBILITY BOSTON SCIENTIFIC SCIMED, INC. (US) 2006-08-10 WO disclosed
US-20060171985-A1 Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility BOSTON SCIENTIFIC SCIMED, INC. 2006-08-03 US disclosed
US-6558808-B1 Heat-sealable, polyolefinic multilayer film, process for the production thereof, and the use thereof BASELL POLYOLEFINE GMBH (DE) 2003-05-06 US disclosed
US-6060139-A Resin-containing, biaxially oriented, multilayer polypropylene film, process for the production thereof, and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 2000-05-09 US disclosed
US-5932157-A Sealable composite polypropylene film and processes for producing and using it HOECHST AKTIENGESELLSCHAFT (DE) 1999-08-03 US disclosed
US-5777055-A Resin-containing, biaxially oriented polypropylene film, process for the production thereof, and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1998-07-07 US disclosed