Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331176 | 1.00 | CCR2 (0.54) | CCR2KCNH2 | |
| SCHEMBL13751300 | 0.86 | CCR2 (0.73) | CCR2KCNH2 | |
| SCHEMBL13613111 | 0.86 | CCR2 (0.73) | CCR2KCNH2 | |
| SCHEMBL13627017 | 0.80 | CCR2 (0.49) | CCR2KCNH2 | |
| SCHEMBL4333182 | 0.76 | KDM5A (0.45) | CCR2KCNH2 | |
| SCHEMBL15760367 | 0.74 | MAP3K12 (0.46) | — | |
| SCHEMBL4331493 | 0.74 | CCR2 (0.75) | CCR2KCNH2 | |
| SCHEMBL4329413 | 0.72 | HCRTR1 (0.45) | KCNH2 | |
| SCHEMBL4340356 | 0.72 | HCRTR1 (0.45) | KCNH2 | |
| SCHEMBL13613110 | 0.72 | CFTR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696919-A4 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1696919-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | Incyte Corporation (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005060665-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |