Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1999647 | 0.85 | HTR6 (0.40) | DRD2DRD3HTR6 | |
| SCHEMBL1997008 | 0.79 | HTR6 (0.43) | DRD2DRD3HTR6 | |
| Trifluoroacetic Acid SCHEMBL4410635 | 0.72 | HTR6 (0.42) | DRD2DRD3HTR6 | |
| Trifluoroacetic Acid SCHEMBL1994879 | 0.72 | KDM4E (0.36) | HTR6 | |
| SCHEMBL1995653 | 0.72 | HTR6 (0.54) | DRD2DRD3HTR6 | |
| SCHEMBL1996842 | 0.72 | HTR6 (0.54) | DRD2DRD3HTR6 | |
| SCHEMBL1999301 | 0.72 | HTR6 (0.54) | DRD2DRD3HTR6 | |
| Trifluoroacetic Acid SCHEMBL1994435 | 0.70 | HTR6 (0.44) | DRD2DRD3HTR6 | |
| Diamide SCHEMBL4711990 | 0.67 | HTR6 (0.46) | DRD2DRD3HTR6 | |
| Trifluoroacetic Acid SCHEMBL4421387 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091953-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4]OXAZEPINO [6, 7-E]INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (publ) (SE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008054288-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4] OXAZEPINO [6, 7-E] INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (PUBL) (SE) | 2008-05-08 | — | — | WO | disclosed |