Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 4/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433247 | 0.73 | CNR1 (0.45) | TRPV1PDE4BPDE4DMEN1KMT2A | |
| SCHEMBL4563433 | 0.72 | KMT2A (0.50) | MEN1KMT2APOLB | |
| SCHEMBL10094698 | 0.69 | TRPV1 (0.64) | TRPV1CYP2A6GAAMETAP2HPGD | |
| SCHEMBL3683921 | 0.68 | KMT2A (0.52) | GAAMEN1HPGDKMT2APOLB | |
| SCHEMBL4562967 | 0.66 | CNR1 (0.44) | MEN1KMT2APOLB | |
| SCHEMBL12857748 | 0.64 | IDO1 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19PDE4B | |
| SCHEMBL29924154 | 0.64 | CYP2A6 (0.61) | TRPV1CYP2A6GAAMETAP2MEN1 | |
| SCHEMBL196235 | 0.64 | CYP2A6 (0.61) | TRPV1CYP2A6GAAMETAP2MEN1 | |
| SCHEMBL31252534 | 0.64 | CYP2A6 (0.61) | TRPV1CYP2A6GAAMETAP2MEN1 | |
| SCHEMBL196840 | 0.63 | CYP2A6 (0.49) | TRPV1CYP2A6SMOPTGS2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026798-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | Solvay Pharmaceuticals GmbH (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007125048-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-08 | — | — | WO | disclosed |