SCHEMBL4562967

SCHEMBL4562967

CCc1cnc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4563433 0.92 KMT2A (0.50) CNR1CNR2KMT2AMEN1POLB
SCHEMBL3683921 0.87 KMT2A (0.52) CNR1CNR2KMT2AMEN1POLB
SCHEMBL12064374 0.85 CNR1 (0.47) CNR1CNR2KMT2AMEN1POLB
SCHEMBL4563346 0.84 KMT2A (0.47) CNR1CNR2KMT2AMEN1POLB
SCHEMBL4562966 0.80 KMT2A (0.49) CNR1CNR2KMT2AMEN1POLB
SCHEMBL4563669 0.79 CNR1 (0.46) CNR1CNR2KMT2AMEN1POLB
SCHEMBL4563366 0.76 KMT2A (0.54) CNR1CNR2KMT2AMEN1POLB
SCHEMBL4563605 0.75 KMT2A (0.47) CNR1CNR2KMT2AMEN1POLB
SCHEMBL4743085 0.72
SCHEMBL4787946 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2026798-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS Solvay Pharmaceuticals GmbH (DE) 2009-02-25 EP disclosed
WO-2007125048-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-08 WO disclosed