Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 18/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431341 | 0.92 | ADRB3 (0.75) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4434448 | 0.89 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4553362 | 0.88 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4429287 | 0.86 | ADRB2 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4441798 | 0.84 | ADRB3 (0.85) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6664676 | 0.84 | ADRB2 (0.77) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4563759 | 0.83 | ADRB3 (0.76) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4553360 | 0.82 | ADRB3 (0.80) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4434321 | 0.81 | ADRB3 (0.75) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4764116 | 0.80 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118086-A1 | ARYLOXYPROPANOLAMINES, METHODS OF PREPARATION THEREOF AND USE OF ARYLOXYPROPANOLAMINES AS MEDICAMENTS | 4SC AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008090140-A1 | ARYLOXYPROPANOLAMINES, METHODS OF PREPARATION THEREOF AND USE OF ARYLOXYPROPANOLAMINES AS MEDICAMENTS | 4SC AG (DE) | 2008-07-31 | — | — | WO | disclosed |