Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.80 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | MMP12 | P39900 | 3/20 | 0.63 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053273 | 1.00 | MMP13 (0.80) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4053281 | 1.00 | MMP13 (0.80) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4057212 | 0.92 | MMP13 (0.71) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4057218 | 0.92 | MMP13 (0.71) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4563778 | 0.92 | MMP13 (0.73) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4051699 | 0.92 | MMP13 (0.73) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4051704 | 0.92 | MMP13 (0.73) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL3973610 | 0.89 | MMP13 (1.00) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4054827 | 0.88 | MMP13 (0.69) | MMP13MMP2MMP12ADAM17 | |
| SCHEMBL4054815 | 0.88 | MMP13 (0.69) | MMP13MMP2MMP12ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | claimed |