Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 15/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062500 | 1.00 | TRPM8 (0.75) | TRPM8 | |
| SCHEMBL3068485 | 0.90 | TRPM8 (0.76) | TRPM8 | |
| SCHEMBL3075245 | 0.86 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL3075402 | 0.85 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL3074708 | 0.84 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL3052085 | 0.80 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL13805596 | 0.78 | TRPM8 (0.75) | TRPM8 | |
| SCHEMBL3052746 | 0.78 | TRPM8 (0.86) | TRPM8 | |
| SCHEMBL3067569 | 0.78 | TRPM8 (0.76) | TRPM8 | |
| SCHEMBL3062678 | 0.78 | TRPM8 (0.76) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073203-A1 | TRP-M8 RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2009-06-11 | — | — | WO | disclosed |