Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969045 | 0.89 | HPGD (0.55) | HPGDSMN1; SMN2NPC1RAB9AF2 | |
| SCHEMBL17747100 | 0.79 | SMN1; SMN2 (0.50) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 | |
| SCHEMBL10735495 | 0.79 | SMN1; SMN2 (0.70) | HPGDSMN1; SMN2NPC1RAB9AF2 | |
| SCHEMBL4295650 | 0.79 | FOLH1 (0.62) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 | |
| SCHEMBL11750017 | 0.79 | NPC1 (0.53) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 | |
| SCHEMBL6895376 | 0.78 | PARP1 (0.57) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 | |
| SCHEMBL1646582 | 0.78 | RXRA (0.56) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 | |
| SCHEMBL131382 | 0.77 | MAOB (0.55) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 | |
| SCHEMBL29066849 | 0.76 | HPGD (0.53) | HPGDSMN1; SMN2NPC1RAB9AF2 | |
| SCHEMBL28979208 | 0.75 | NPC1 (0.53) | HPGDSMN1; SMN2NPC1RAB9ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032546-A3 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012032546-A2 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |