Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.67 |
| ▸ | MMP13 | P45452 | 16/20 | 0.67 |
| ▸ | MMP3 | P08254 | 12/20 | 0.67 |
| ▸ | MMP1 | P03956 | 6/20 | 0.67 |
| ▸ | MMP9 | P14780 | 4/20 | 0.65 |
| ▸ | MMP8 | P22894 | 2/20 | 0.65 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564383 | 1.00 | MMP2 (0.67) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL22787772 | 0.90 | MMP2 (0.55) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7511957 | 0.86 | MMP2 (0.60) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4333373 | 0.85 | MMP2 (0.64) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4333378 | 0.85 | MMP2 (0.64) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL13570807 | 0.83 | MMP2 (0.62) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL13570499 | 0.83 | MMP2 (0.62) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4619626 | 0.83 | MMP2 (0.66) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4621504 | 0.83 | MMP2 (0.66) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4620929 | 0.83 | MMP2 (0.66) | MMP2MMP13MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612060-B2 | Triazoles and methods of use | AMGEN INC. (US) | 2009-11-03 | — | — | US | disclosed |