Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141876 | 0.87 | GABRA1 (0.45) | GABRA1GABRB2AKR1B1KDM4EAURKA | |
| SCHEMBL3281815 | 0.82 | — | — | |
| SCHEMBL811836 | 0.79 | — | — | |
| SCHEMBL8010806 | 0.79 | HSPA5 (0.34) | — | |
| SCHEMBL29900352 | 0.78 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1KDM4EALDH1A1 | |
| SCHEMBL2362466 | 0.78 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1KDM4EALDH1A1 | |
| SCHEMBL251882 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2AKR1B1KDM4EALDH1A1 | |
| SCHEMBL6805441 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2AKR1B1KDM4EALDH1A1 | |
| SCHEMBL3452372 | 0.76 | — | — | |
| SCHEMBL11380312 | 0.76 | GABRA1 (0.43) | GABRA1GABRB2AKR1B1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105238360-B | Working fluid composition for refrigerator and refrigerator oil | 吉坤日矿日石能源株式会社 | 2020-05-05 | — | — | CN | claimed |
| EP-2134781-A1 | USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS | Albemarle Corporation (US) | 2009-12-23 | — | — | EP | claimed |
| WO-2008118699-A1 | USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS | ALBEMARLE CORPORATION (US) | 2008-10-02 | — | — | WO | claimed |
| EP-0395313-B1 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PROD (US) | 1999-12-15 | — | — | EP | claimed |
| US-5182273-A | Antitumor, anticancer | PIERRE FABRE MEDICAMENT (FR) | 1993-01-26 | — | — | US | claimed |
| WO-2023109387-A1 | COUPLING OF SULFYDRYL-CONTAINING PEPTIDE AND FLUOROPORPHYRIN AS BIOLOGICAL PROBE | 化学与精细化工广东省实验室 | 2023-06-22 | — | — | WO | disclosed |
| WO-2020158205-A1 | SULFUR-CONTAINING EXTREME-PRESSURE AGENT AND METAL WORKING OIL | DIC株式会社 | 2020-08-06 | — | — | WO | disclosed |
| CN-105238360-B | Working fluid composition for refrigerator and refrigerator oil | 吉坤日矿日石能源株式会社 | 2020-05-05 | — | — | CN | disclosed |