SCHEMBL4564485

SCHEMBL4564485

Clc1cc(-c2ccccc2)c(Cl)c(SSc2c(Cl)c(Cl)cc(-c3ccccc3)c2Cl)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.45
AHR P35869 4/20 0.44
CSNK2A1 P68400 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSP90AA1 P07900 1/20 0.38
BACE1 P56817 1/20 0.37
ESR2 Q92731 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CTRC Q99895 2/20 0.32
ALOX5 P09917 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL404196 0.79 AHR (0.68) CYP2A6AHRCSNK2A1MEN1KMT2A
SCHEMBL29422942 0.79 AHR (0.68) CYP2A6AHRCSNK2A1MEN1KMT2A
Methane SCHEMBL27372843 0.77 AHR (0.65) CYP2A6AHRCSNK2A1MEN1KMT2A
SCHEMBL10596187 0.77 AHR (0.65) CYP2A6AHRCSNK2A1MEN1KMT2A
Water SCHEMBL11700413 0.77 AHR (0.65) CYP2A6AHRCSNK2A1MEN1KMT2A
SCHEMBL2466770 0.73 CYP2A6 (0.46) CYP2A6AHRCSNK2A1MEN1KMT2A
SCHEMBL27902954 0.73 CYP2A6 (0.46) CYP2A6AHRCSNK2A1MEN1KMT2A
SCHEMBL2140618 0.72 CYP2A6 (0.50) CYP2A6AHRCSNK2A1MEN1KMT2A
SCHEMBL260696 0.72 CYP3A4 (0.53) AHRMEN1KMT2AHSP90AA1ESR2
SCHEMBL5159779 0.71 CYP2A6 (0.48) CYP2A6AHRCSNK2A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8642718-B2 Curable composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-02-04 US disclosed
EP-1882713-B1 CURABLE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2013-07-03 EP disclosed
US-20090018308-A1 Curable Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-01-15 US disclosed
EP-1882713-A1 CURABLE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-01-30 EP disclosed