SCHEMBL260696

SCHEMBL260696

Clc1cc(Cl)c(Cl)c(SSc2c(Cl)c(Cl)cc(Cl)c2Cl)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.53
HPGD P15428 7/20 0.45
HSD17B10 Q99714 7/20 0.45
TSHR P16473 7/20 0.45
CASP1 P29466 1/20 0.45
ALDH1A1 P00352 3/20 0.42
MAPK1 P28482 3/20 0.41
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
AHR P35869 8/20 0.38
HSP90AA1 P07900 2/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
USP2 O75604 1/20 0.35
EGFR P00533 1/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.35
ERBB2 P04626 1/20 0.35
CYP1A2 P05177 1/20 0.35
LCK P06239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1646162 0.94 CYP3A4 (0.56) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL6518691 0.81 CYP3A4 (0.56) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL1645523 0.77 CYP3A4 (0.38) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL27993900 0.75 CYP3A4 (0.47) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL11765509 0.73 CYP3A4 (0.45) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL4564485 0.72 CYP2A6 (0.45) HPGDALDH1A1AHRHSP90AA1MEN1
SCHEMBL1646060 0.71 ALDH1A1 (0.48) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL16312913 0.71 CYP3A4 (0.43) CYP3A4HPGDHSD17B10TSHRCASP1
SCHEMBL9194802 0.71 CYP3A4 (0.39) CYP3A4TSHRMAPK1AHRLMNA
SCHEMBL224297 0.70 MEN1 (0.31) HPGDHSD17B10TSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US claimed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-20250018250-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-01-16 US disclosed
US-20240299812-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-09-12 US disclosed
US-20240269520-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-08-15 US disclosed
US-11712605-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-08-01 US disclosed
US-20230060884-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-03-02 US disclosed
US-20230054484-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-02-23 US disclosed
US-11583734-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-02-21 US disclosed
US-11583733-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-02-21 US disclosed
US-20070049421-A1 Golf ball SRI SPORTS LIMITED 2007-03-01 US disclosed
US-6835793-B2 Isocyanate group-terminated urethane prepolymer and an aromatic polyamine compound covering with thickness of from .2-.5 mm, shore d hardness of 30-55 and a deformation amount is 2.4-3.3 mm when applying a load of 98-1275 n SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2004-12-28 US disclosed
US-20030120020-A1 Golf ball having a polyurethane cover SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-06-26 US disclosed
US-20030114246-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2003-06-19 US disclosed
EP-0402481-B1 PRODUCTION OF POLYARYLENE THIOETHER PROD DEV RES INST (JP) 1995-10-25 EP disclosed
US-5290911-A Forming polymers by catalytic oxidative coupling RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1994-03-01 US disclosed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US disclosed
US-4983720-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-01-08 US disclosed
EP-0402481-A1 PRODUCTION OF POLYARYLENE THIOETHER RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1990-12-19 EP disclosed
US-4931542-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) 1990-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 CYP3A4 4002/4885HPGD 1169/4885HSD17B10 1594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.