Cyclohexanone

Cyclohexanone

SCHEMBL4564591

O=C1CCCCC1.c1ccccc1

nearest known ligand 0.79

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.79
TRIM24 O15164 2/20 0.79
TRIM33 Q9UPN9 2/20 0.79
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CYP2C9 P11712 1/20 0.40
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CFTR P13569 1/20 0.33
GOPC Q9HD26 1/20 0.33
ESR2 Q92731 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentanone SCHEMBL28251672 0.96 TRIM24 (0.77) ALDH1A1TRIM24TRIM33MEN1KMT2A
Cyclopentanone SCHEMBL28121980 0.93 TRIM24 (0.71) ALDH1A1TRIM24TRIM33MEN1KMT2A
Cyclohexanone SCHEMBL375072 0.89
SCHEMBL1905857 0.89 TRIM24 (1.00) ALDH1A1TRIM24TRIM33KMT2ATSHR
Cyclohexanone SCHEMBL3299 0.89
SCHEMBL25380098 0.89 TRIM24 (1.00) ALDH1A1TRIM24TRIM33KMT2ATSHR
SCHEMBL112034 0.89 TRIM24 (1.00) ALDH1A1TRIM24TRIM33KMT2ATSHR
Cycloheptanone SCHEMBL6077 0.89
SCHEMBL3396727 0.89 TRIM24 (1.00) ALDH1A1TRIM24TRIM33KMT2ATSHR
Cyclohexanone SCHEMBL713141 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905811-A A kind of hydrophobic coating for base material and preparation method thereof 北京奥托米特电子有限公司 2017-06-30 CN claimed
US-20140350240-A1 PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF RANBAXY LABORATORIES LIMITED (IN) 2014-11-27 US claimed
EP-2788361-A1 PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF Ranbaxy Laboratories Limited (IN) 2014-10-15 EP claimed
WO-2013084171-A1 PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF RANBAXY LABORATORIES LIMITED (IN) 2013-06-13 WO claimed
CN-216703393-U Crude benzene diverging device of cyclohexane dehydrogenation 福建永荣科技有限公司 2022-06-10 CN disclosed
CN-212356526-U Recovery unit of hydrogen-containing tail gas in caprolactam production technology 湖北三宁化工股份有限公司 2021-01-15 CN disclosed
CN-110531582-A Hardening resin composition and application thereof NIPPON CATALYTIC CHEM IND 2019-12-03 CN disclosed
CN-103576457-B Curable resin composition and use thereof 株式会社日本触媒 2019-10-25 CN disclosed
CN-106348994-B The method and device that a kind of pair of cyclohexanone dehydrogenation gas is pressurized 湖北三宁化工股份有限公司 2019-09-24 CN disclosed
CN-106348997-B The method and device of transition metal in a kind of removal hexamethylene 湖北三宁化工股份有限公司 2019-09-24 CN disclosed
CN-109384903-A Aqueous polyurethane resin dispersion and its manufacturing method 宇部兴产株式会社 2019-02-26 CN disclosed
CN-106132876-B The composition and cosmetic of silica coating zinc oxide and its manufacturing method, the coating zinc oxide containing silica 住友大阪水泥株式会社 2018-12-28 CN disclosed
CN-103180326-A Heterocyclic compounds and their use TAKEDA PHARMACEUTICAL 2013-06-26 CN disclosed
CN-202609924-U Pure hydrogen diversion device in gas mixture hydrogen extraction section of synthetic ammonia SHANDONG HONGDA CHEMICAL CO LTD 2012-12-19 CN disclosed
EP-2094635-A1 CARBONYLATION OF CONJUGATED DIENES Lucite International UK Limited (GB) 2009-09-02 EP disclosed
WO-2008075108-A1 CARBONYLATION OF CONJUGATED DIENES LUCITE INTERNATIONAL UK LIMITED (GB) 2008-06-26 WO disclosed
US-5180871-A Process for producing phenols MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-01-19 US disclosed
EP-0316142-A2 Process for producing phenols MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-05-17 EP disclosed
US-3994851-A AMINE-ALDEHYDE CROSSLINKING AGENT PPG INDUSTRIES, INC. (US) 1976-11-30 US disclosed
US-3987196-A FUNGISTATS ELI LILLY AND COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350240-A1 PROCESS FOR PREPARING CEFTAROLINE SALTS OR HYDRATES THEREOF CYP3A7, SEPTIN7, UGT1A7 ALDH1A1 2155/4885TRIM24 3820/4885TRIM33 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.