Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 11/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538355 | 0.82 | MLYCD (1.00) | MLYCD | |
| SCHEMBL647994 | 0.70 | MLYCD (1.00) | MLYCD | |
| SCHEMBL1897781 | 0.69 | MLYCD (0.86) | MLYCD | |
| SCHEMBL1896871 | 0.66 | MLYCD (0.81) | MLYCD | |
| SCHEMBL1899914 | 0.66 | MLYCD (0.80) | MLYCD | |
| SCHEMBL10044255 | 0.65 | MLYCD (0.80) | MLYCD | |
| SCHEMBL1900991 | 0.65 | MLYCD (1.00) | MLYCD | |
| SCHEMBL4496977 | 0.64 | MLYCD (0.72) | MLYCD | |
| SCHEMBL7236313 | 0.63 | NSD2 (0.71) | MLYCDMEN1NPC1KMT2ANSD2 | |
| SCHEMBL1899912 | 0.62 | MLYCD (0.72) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524969-B2 | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-28 | — | — | US | claimed |