Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565162 | 0.76 | PPARA (0.43) | SCDPPARDPPARAPPARG | |
| SCHEMBL243871 | 0.72 | SCD (0.60) | SCDPPARDPPARAPPARG | |
| SCHEMBL347133 | 0.68 | SCD (0.70) | SCDPPARDPPARAPPARG | |
| SCHEMBL347554 | 0.67 | SCD (1.00) | SCD | |
| SCHEMBL245124 | 0.67 | SCD (0.76) | SCD | |
| SCHEMBL242868 | 0.67 | SCD (0.56) | SCDPPARDPPARAPPARG | |
| SCHEMBL1909733 | 0.65 | SCD (0.52) | SCDPPARDPPARAPPARG | |
| SCHEMBL1576766 | 0.65 | HSD17B3 (0.51) | SCDPPARDPPARAPPARG | |
| SCHEMBL1569155 | 0.64 | KDM5A (0.58) | SCDPPARDPPARAPPARG | |
| SCHEMBL12464377 | 0.64 | SCD (0.82) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054408-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | Novartis Ag (CH) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |