SCHEMBL4565241

SCHEMBL4565241

CC(C)(C)c1cc(Cc2ccccc2)cc(C(C)(C)C)c1O.Cc1cc(Cc2ccccc2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.64
CYP2C9 P11712 2/20 0.62
CYP2C19 P33261 2/20 0.62
HIF1A Q16665 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
CYP2D6 P10635 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ALDH1A1 P00352 2/20 0.51
CA2 P00918 1/20 0.51
POLB P06746 1/20 0.51
TYR P14679 1/20 0.51
GAA P10253 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
PTPN1 P18031 2/20 0.46
PTPN2 P17706 1/20 0.46
PTPN6 P29350 1/20 0.46
BCL2 P10415 1/20 0.45
BCL2L1 Q07817 1/20 0.45
DHFR P00374 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459522 0.94 HSPA5 (0.72) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL9817016 0.90 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8772330 0.89 HSPA5 (0.79) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8047562 0.88 HSPA5 (0.83) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL12430324 0.86 HSPA5 (0.65) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1187217 0.86 MEN1 (0.57) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL5179089 0.86 CYP2C9 (0.49) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4456953 0.85 HSPA5 (0.59) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL11568213 0.83 HIF1A (0.77) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL9950640 0.83 HSPA5 (0.79) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524621-B2 Method of preparing silver carboxylate soaps CARESTREAM HEALTH, INC. (US) 2009-04-28 US disclosed
EP-1910895-B1 THERMALLY DEVELOPABLE MATERIALS WITH ABRASION-RESISTANT BACKSIDE COATINGS CARESTREAM HEALTH INC (US) 2008-12-10 EP disclosed
US-7452661-B2 Photothermographic materials incorporating antifoggants CARESTREAM HEALTH, INC. (US) 2008-11-18 US disclosed
US-20080206688-A1 PHOTOTHERMOGRAPHIC MATERIALS INCORPORATING ANTIFOGGANTS QUANTUM MEDICAL IMAGING, L.L.C. 2008-08-28 US disclosed
US-7371709-B2 Thermally developable materials with backside antistatic layer TROPHY DENTAL INC. 2008-05-13 US disclosed
EP-1910895-A1 THERMALLY DEVELOPABLE MATERIALS WITH ABRASION-RESISTANT BACKSIDE COATINGS Carestream Health, Inc. (US) 2008-04-16 EP disclosed
US-7267935-B1 Thermally developable materials stabilized with crown ethers CARESTREAM HEALTH, INC. (US) 2007-09-11 US disclosed
US-7261999-B2 Photothermographic materials containing post-processing stabilizers CARESTREAM HEALTH, INC. (US) 2007-08-28 US disclosed
US-7258967-B1 Photothermographic materials containing print stabilizers CARESTREAM HEALTH, INC. (US) 2007-08-21 US disclosed
WO-2007092242-A1 PHOTOTHERMOGRAPHIC REDUCING AGENTS WITH BICYCLIC OR TRICYCLIC SUBSTITUTION CARESTREAM HEALTH, INC. (US) 2007-08-16 WO disclosed
US-20070190468-A1 PHOTOTHERMOGRAPHIC MATERIALS INCORPORATING ARYLBORONIC ACIDS EASTMAN KODAK COMPANY 2007-08-16 US disclosed
US-7241561-B1 Photothermographic reducing agents with bicyclic or tricyclic substitution CARESTREAM HEALTH, INC. (US) 2007-07-10 US disclosed
US-20070117053-A1 Photothermographic materials containing post-processing stabilizers EASTMAN KODAK COMPANY 2007-05-24 US disclosed
US-20070072772-A1 Thermally developable materials with backside antistatic layer EASTMAN KODAK COMPANY 2007-03-29 US disclosed
WO-2007015963-A1 THERMALLY DEVELOPABLE MATERIALS WITH ABRASION-RESISTANT BACKSIDE COATINGS CARESTREAM HEALTH, INC. (US) 2007-02-08 WO disclosed
US-7153636-B1 Thermally developable materials with abrasion-resistant backside coatings EASTMAN KODAK COMPANY (US) 2006-12-26 US disclosed