SCHEMBL8772330

SCHEMBL8772330

Cc1cc(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.79
HIF1A Q16665 5/20 0.77
CYP2C9 P11712 4/20 0.77
CYP2C19 P33261 4/20 0.77
SMN1; SMN2 Q16637 4/20 0.77
CYP2D6 P10635 2/20 0.68
HSD17B10 Q99714 1/20 0.68
ALDH1A1 P00352 8/20 0.64
CA2 P00918 2/20 0.64
POLB P06746 1/20 0.64
TYR P14679 1/20 0.64
DHFR P00374 1/20 0.50
TSHR P16473 3/20 0.49
LMNA P02545 2/20 0.49
GAA P10253 1/20 0.49
MAPK1 P28482 3/20 0.47
MEN1 O00255 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
BLM P54132 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8047562 0.95 HSPA5 (0.83) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL9950640 0.93 HSPA5 (0.79) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL12309158 0.93 HSPA5 (0.79) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL11568213 0.93 HIF1A (0.77) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL4565241 0.89 HSPA5 (0.64) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
Butylated Hydroxytoluene SCHEMBL1000655 0.89 ALDH1A1 (0.75) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL29415372 0.89 HSPA5 (1.00) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL34162 0.89 HSPA5 (1.00) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL29351672 0.89 HSPA5 (1.00) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL20596953 0.88 HSPA5 (0.78) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208264-B2 Photothermographic material and method of forming images FUJIFILM CORPORATION (JP) 2007-04-24 US disclosed
US-7208264-B2 Photothermographic material and method of forming images FUJIFILM CORPORATION (JP) 2007-04-24 US disclosed
US-7192695-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-03-20 US disclosed
US-7192695-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-03-20 US disclosed
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5409798-A Base layer containing polymerizable compound, photosensitive layer capable of peeling development containing different polymerizable compound, layer-forming polymer, photoinitiator, peeling support layer CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
EP-0530674-A1 Plate blank, process for producing printing plate from plate blank, and printing method and apparatus using plate CANON KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed