Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709760 | 1.00 | ROCK2 (0.39) | ROCK2ROCK1 | |
| SCHEMBL3706764 | 0.87 | PSEN1 (0.36) | — | |
| SCHEMBL3706768 | 0.87 | PSEN1 (0.36) | — | |
| SCHEMBL3707149 | 0.84 | PSEN1 (0.37) | — | |
| SCHEMBL3716564 | 0.83 | BRD4 (0.34) | — | |
| SCHEMBL3716567 | 0.83 | BRD4 (0.34) | — | |
| SCHEMBL3702628 | 0.83 | IRAK4 (0.32) | — | |
| SCHEMBL3708508 | 0.79 | SCD (0.35) | ROCK2 | |
| SCHEMBL3709120 | 0.78 | PSEN1 (0.46) | — | |
| SCHEMBL3709129 | 0.78 | PSEN1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064269-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF Αβ-RELATED DISEASES | ASTRAZENECA AB (SE) | 2012-05-18 | — | — | WO | disclosed |