Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565446 | 1.00 | EPHX1 (0.53) | EPHX1HPGDABL1RIN1ALDH1A1 | |
| SCHEMBL23726871 | 0.81 | EPHX1 (0.59) | EPHX1HPGDABL1RIN1ALDH1A1 | |
| SCHEMBL31722057 | 0.80 | EPHX1 (0.60) | EPHX1HPGDALDH1A1MAPTCA1 | |
| SCHEMBL25656195 | 0.80 | EPHX1 (0.60) | EPHX1HPGDALDH1A1MAPTCA1 | |
| SCHEMBL4236015 | 0.79 | ALDH1A1 (0.39) | EPHX1ALDH1A1CA1CA2SFRP1 | |
| SCHEMBL31722556 | 0.78 | EPHX1 (0.58) | EPHX1HPGDALDH1A1MEN1MAPT | |
| SCHEMBL23758482 | 0.78 | EPHX1 (0.61) | EPHX1HPGDALDH1A1MEN1MAPT | |
| SCHEMBL28610943 | 0.77 | EPHX1 (0.56) | EPHX1HPGDALDH1A1MAPTCA1 | |
| SCHEMBL21664372 | 0.75 | EPHX1 (0.50) | EPHX1HPGDALDH1A1MEN1MAPT | |
| SCHEMBL30636984 | 0.75 | EPHX1 (0.50) | EPHX1HPGDALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069347-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | Merck & Co., Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008039420-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-04-03 | — | — | WO | disclosed |