Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 18/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565079 | 0.86 | SLC6A2 (0.40) | SLC6A2SLC6A3SLC6A4KCNH2HRH3 | |
| SCHEMBL3607020 | 0.76 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL3608735 | 0.76 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4064766 | 0.75 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL3598010 | 0.70 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4565249 | 0.70 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3616900 | 0.70 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL3617241 | 0.70 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL3608625 | 0.70 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL3595496 | 0.69 | SLC6A2 (0.60) | SLC6A2SLC6A3SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |