Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387304 | 0.87 | P2RY12 (0.46) | P2RY12PTGDR2MEN1KMT2ANPC1 | |
| SCHEMBL4381786 | 0.86 | DPP4 (0.39) | DPP4DPP8RIPK3RORCGRM5 | |
| SCHEMBL4385524 | 0.84 | POLB (0.42) | DPP4DPP8RORCGRM5MEN1 | |
| SCHEMBL13589008 | 0.83 | KMT2A (0.42) | P2RY12DPP4DPP8KMT2ANPC1 | |
| SCHEMBL4382790 | 0.82 | PTGDR2 (0.42) | DPP4DPP8RORCPTGDR2KMT2A | |
| SCHEMBL4382741 | 0.82 | DPP4 (0.36) | DPP4DPP8RIPK3RORCGRM1 | |
| SCHEMBL4384414 | 0.81 | S1PR3 (0.36) | P2RY12DPP4DPP8RIPK3RORC | |
| SCHEMBL4376868 | 0.81 | DPP4 (0.36) | DPP4DPP8RIPK3RORCGRM1 | |
| SCHEMBL4387758 | 0.81 | FKBP1A (0.45) | DPP4DPP8PTGDR2MEN1KMT2A | |
| SCHEMBL4380717 | 0.80 | GPR183 (0.46) | MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |