SCHEMBL456612

SCHEMBL456612

C[SiH](C)C1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5461637 1.00 CES2 (0.33)
SCHEMBL5478088 1.00 CES2 (0.33)
SCHEMBL6027162 1.00 CES2 (0.33)
SCHEMBL6026907 1.00 CES2 (0.33)
SCHEMBL3771984 1.00 CES2 (0.33)
SCHEMBL5477820 1.00 CES2 (0.33)
SCHEMBL5468555 1.00 CES2 (0.33)
Hydrochloric Acid SCHEMBL29767780 0.97 CES2 (0.32)
SCHEMBL3149818 0.96
SCHEMBL1539348 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 563 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170283368-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS PARATEK PHARMACEUTICALS, INC. 2017-10-05 US claimed
CN-105017737-B Polypropylene-polyester-carbon nano tube ternary composite alloy and preparation method thereof 中国科学院化学研究所 2017-01-18 CN claimed
US-7736634-B2 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2010-06-15 US claimed
US-20100099875-A1 NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS PHOSPHOENIX SARL (FR) 2010-04-22 US claimed
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-20080075973-A1 Red Electroluminescent Compounds And Organic Electroluminescent Device Using The Same GRACEL DISPLAY INC. (KR) 2008-03-27 US claimed
US-20070129331-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES RND PHARMACEUTICALS, INC. (US) 2007-06-07 US claimed
EP-1737471-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES RND Pharmaceuticals (US) 2007-01-03 EP claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
EP-1558654-A4 NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF FUJIFILM ELECTRONIC MATERIALS (US) 2006-04-05 EP claimed
WO-1995013095-A2 THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1995-05-18 WO claimed
WO-1995007894-A1 SUBSTITUTED PYRIDINES AND PYRIMIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO claimed
WO-1994021613-A1 CONDENSED NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS, FUNGICIDES AND ANTIMYCOTICS HOECHST SCHERING AGREVO GMBH (DE) 1994-09-29 WO claimed
US-5294737-A Hydrolysis, cyclization, condensation THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) 1994-03-15 US claimed
EP-0431480-A2 Substituted 10-ring-lactones, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-12 EP claimed
US-5011827-A Elaiophyline derivatives, compositions containing them and the use thereof as anthelmintic agents HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-30 US claimed
EP-0358177-A1 Medicine with a synergistic antimycosic and antiviral activity HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-14 EP claimed
EP-0346760-A2 Derivatives of nigericine, methods for their preparation, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-12-20 EP claimed
EP-0339444-A1 Elaiophylin derivatives, process for their preparation and use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1989-11-02 EP claimed
EP-0315003-A2 Elaiophylin derivatives, method for their preparation, product containing them and its use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-10 EP claimed