SCHEMBL456614

SCHEMBL456614

c1ccc(CCCCOCCCCCCNCc2ccccc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.80
MAOA P21397 1/20 0.67
CHRM2 P08172 1/20 0.65
BCHE P06276 2/20 0.61
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
CNR1 P21554 1/20 0.54
CNR2 P34972 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9254084 0.98 SIGMAR1 (0.77) SIGMAR1MAOACHRM2BCHEGAA
Bromide SCHEMBL7121198 0.98 SIGMAR1 (0.77) SIGMAR1MAOACHRM2BCHEGAA
SCHEMBL27496896 0.98 SIGMAR1 (0.77) SIGMAR1MAOACHRM2BCHEGAA
Hydrochloric Acid SCHEMBL9257562 0.98 SIGMAR1 (0.77) SIGMAR1MAOACHRM2BCHEGAA
Hydrochloric Acid SCHEMBL454214 0.98 SIGMAR1 (0.77) SIGMAR1MAOACHRM2BCHEGAA
Hydrochloric Acid SCHEMBL9254761 0.97 SIGMAR1 (0.77) SIGMAR1MAOACHRM2BCHEGAA
SCHEMBL9666404 0.97 SIGMAR1 (0.74) SIGMAR1MAOACHRM2BCHEGAA
Hydrochloric Acid SCHEMBL9260556 0.95 SIGMAR1 (0.72) SIGMAR1MAOACHRM2BCHEGAA
Bromide SCHEMBL9578037 0.95 SIGMAR1 (0.72) SIGMAR1MAOACHRM2BCHEGAA
SCHEMBL10477755 0.93 SIGMAR1 (0.69) SIGMAR1MAOACHRM2BCHEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120155983-A Aldehyde-free shaving board and preparation method and application thereof 万华化学(北京)有限公司 2025-06-17 CN claimed
CN-105884625-A synthetic method of R-salmeterol 浙江工业大学 2016-08-24 CN claimed
CN-103420856-B Salmeterol preparation method ASYMCHEM LAB TIANJIN CO LTD 2015-07-01 CN claimed
CN-103641727-A Method for preparing salmeterol xinafoate SHANDONG YONGTAI CHEMICAL CO 2014-03-19 CN claimed
CN-1056974-C Drug material suitable for micronisation GLAXO GROUP LTD (GB) 2000-10-04 CN claimed
CN-120155983-A Aldehyde-free shaving board and preparation method and application thereof 万华化学(北京)有限公司 2025-06-17 CN disclosed
CN-119970731-A Inhalation dry powder preparation containing salmeterol and tiotropium salt composition and preparation method thereof 南昌弘益科技有限公司 2025-05-13 CN disclosed
CN-105884625-B Synthetic method of R-salmeterol 浙江工业大学 2018-11-13 CN disclosed
WO-2017168431-A1 PROCESS FOR THE PREPARATION OF SALMETEROL XINAFOATE DAVULURI RAMAMOHAN RAO (IN) 2017-10-05 WO disclosed
CN-106588633-A Crystal of fumarate of salmeterol intermediate and preparation process thereof 江苏恒盛药业有限公司 2017-04-26 CN disclosed
CN-102458364-B Compositions for pulmonary delivery of long-acting muscarinic antagonists and long-acting beta 2 adrenergic receptor agonists, and related methods and systems 珍珠治疗公司 2016-11-02 CN disclosed
CN-105884625-A synthetic method of R-salmeterol 浙江工业大学 2016-08-24 CN disclosed
US-4943591-A TREATMENT OF ASTHMA AND BRONCHITIS GLAXO GROUP LIMITED (GB) 1990-07-24 US disclosed
EP-0181709-B1 DICHLOROANILINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1990-05-09 EP disclosed
US-4908386-A Pharmaceuticals GLAXO GROUP LIMITED (GB) 1990-03-13 US disclosed
US-4853381-A Ethanolamine compounds GLAXO GROUP LIMITED (GB) 1989-08-01 US disclosed
EP-0162576-B1 ETHANOLAMINE COMPOUNDS GLAXO GROUP LIMITED (GB) 1989-07-26 EP disclosed
EP-0220054-A2 Ethanolamine derivatives GLAXO GROUP LIMITED (GB) 1987-04-29 EP disclosed
EP-0181709-A1 Dichloroaniline Derivatives GLAXO GROUP LIMITED (GB) 1986-05-21 EP disclosed
EP-0162576-A1 Ethanolamine compounds GLAXO GROUP LIMITED (GB) 1985-11-27 EP disclosed